Self-experimenters and startup founders who turned body optimization into business empires.
The Biohacker Billionaire Path
Biohackers approach the body like software—something to be optimized, upgraded, and debugged. The wealthiest figures in this category often made their money elsewhere (tech exits, investing) before dedicating resources to longevity research. Others built supplement empires and media platforms around their self-experimentation.
This hub tracks biohacker net worth alongside wellness startup founders. These figures differ from physician-entrepreneurs: they lead with personal experimentation rather than clinical credentials. Their willingness to try unproven interventions on themselves—and document the results—creates both devoted followers and significant controversy.
Return to the Master Health Guru Net Worth Index for complete rankings.
Top-Earning Biohackers & Founders
| Name | Est. Net Worth | Wealth Source | Biohacking Focus | Profile |
|---|---|---|---|---|
| Bryan Johnson | $400-600M | Braintree/Venmo exit | Blueprint anti-aging protocol | View → |
| Tim Ferriss | $100M | Uber investment, books, podcast | Self-experimentation, lifestyle design | View → |
| Dave Asprey | $50-100M | Bulletproof Coffee, Upgrade Labs | Cognitive enhancement, biohacking franchises | View → |
| Calley Means | $10-20M | Truemed founder, policy influence | Metabolic health policy | View → |
| Eric Berg | $10-15M | YouTube empire, supplements | Keto, intermittent fasting | View → |
| Ben Greenfield | $5-8M | Kion supplements, Boundless | Extreme athletic optimization | View → |
| Mindy Pelz | $3-8M | Fast Like a Girl, YouTube | Women’s fasting protocols | View → |
| Max Lugavere | $2-4M | Genius Foods, podcast | Brain health optimization | View → |
| Shawn Baker | $2-5M | MeatRx, Carnivore Diet | All-meat eating, athletic records | View → |
How Biohackers Build Wealth
Tech Exit → Biohacking Focus
Bryan Johnson made his fortune selling Braintree to PayPal for $800 million. Now he spends $2+ million annually on his Blueprint longevity protocol. Tim Ferriss built wealth through early investments in Uber, Shopify, and Facebook before focusing on self-optimization content. This pathway provides capital to fund expensive interventions while building media platforms.
Supplement Empires
Dave Asprey’s Bulletproof Coffee became a cultural phenomenon, spawning a product line and franchise business (Upgrade Labs). Ben Greenfield’s Kion sells amino acids, coffee, and performance supplements. These direct-to-consumer businesses generate recurring revenue with strong margins.
Content-First Monetization
Eric Berg built 13.5 million YouTube subscribers through daily keto content. Tim Ferriss’ podcast generates $50,000-100,000 per episode in sponsorships. Content creates audience; audience enables product sales and premium pricing.
Health Tech Equity
Founders of wellness technology companies capture value through equity stakes. Casey Means’ Levels Health stake, Calley Means’ Truemed ownership—these represent paper wealth that can convert to cash through exits or secondary sales.
The Self-Experimentation Credibility Model
Biohackers build trust differently than physicians. Instead of credentials, they offer transparency about personal experimentation:
- Bryan Johnson: Publishes all biomarkers, protocols, and results. Documents everything from sleep scores to biological age tests.
- Ben Greenfield: Tests supplements, devices, and protocols on himself before recommending. Documents failures alongside successes.
- Tim Ferriss: “Guinea pig” approach—tries everything from ice baths to psychedelics and reports results.
- Dave Asprey: Claims to have spent $1 million on biohacking experiments. Built Bulletproof on personal cognitive enhancement quest.
This approach creates devoted followers who trust recommendations because they’ve watched the experimenter try things first. It also attracts criticism when self-experimentation gets positioned as evidence for what others should do.
Controversies in Biohacking
Self-experimentation without medical oversight generates controversy:
- Bryan Johnson: Young blood transfusions, extreme calorie restriction, 100+ daily supplements. Critics question sustainability and applicability to normal humans.
- Dave Asprey: Some Bulletproof claims lack rigorous scientific backing. His promotion of butter-in-coffee drew nutrition criticism.
- Eric Berg: Chiropractor advising on nutrition without formal training. Some medical professionals question qualifications.
- Shawn Baker: Medical license issues. Carnivore diet contradicts virtually all nutritional guidelines.
Supporters argue biohackers are pioneers willing to push boundaries that cautious medicine won’t explore. Critics contend they’re selling unproven interventions using charisma rather than evidence.